Article
Predicting non-response to ranibizumab in patients with neovascular age-related macular degeneration.
Ophthalmic epidemiology - 1 Dec 2014
van Asten Freekje, Rovers Maroeska M, Lechanteur Yara T E, Smailhodzic Dzenita, Muether Philipp S, Chen John, den Hollander Anneke I, Fauser Sascha, Hoyng Carel B, van der Wilt Gert Jan, Klevering B Jeroen
Abstract excerpt
PURPOSE: To validate known and determine new predictors of non-response to ranibizumab in patients with neovascular age-related macular degeneration (AMD) and to incorporate these factors into a prediction rule. METHODS: This multicenter, observational cohort study included 391 patients treated with ranibizumab for neovascular AMD. We performed genetic analysis for single nucleotide polymorphisms in...
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