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Article

The associations of hub gene polymorphisms in PI3K/AKT/mTOR pathway and Schistosomiasis Japonica infection and hepatic fibrosis.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2020

Xiao Qin, Yu Haibing, Zhu Xiao

Abstract excerpt

INTRODUCTION: Increasing evidence shows that the PI3K/AKT/mTOR pathway can be activated by a variety of stimulus in immune cells. Schistosomiasis Japonica is a serious threat to human health in some lakes of China. METHODS: We analyzed the potential associations between the hub gene (PTEN, mTOR, AKT1 and AKT2) polymorphisms of PI3K/AKT/mTOR pathway and S. japonica risk, including infection risk, as well as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32554084
DOI: 10.1016/j.meegid.2020.104423

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