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Article

MiR-181b sensitizes glioma cells to teniposide by targeting MDM2

25 Aug 2014

Abstract excerpt

BACKGROUND: Although the incidence of glioma is relatively low, it is the most malignant tumor of the central nervous system. The prognosis of high-grade glioma patient is very poor due to the difficulties in complete resection and resistance to radio-/chemotherapy. Therefore, it is worth investigating the molecular mechanisms involved in glioma drug resistance. MicroRNAs have been found to play important roles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25151861
DOI: 10.1186/1471-2407-14-611

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