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Article

Epidermal growth factor receptor (EGFR) exon 20 mutations in non-small-cell lung cancer and resistance to EGFR-tyrosine kinase inhibitors.

Investigational new drugs - 1 Dec 2014

Woo Hyun Sun, Ahn Hee Kyung, Lee Ha Yeon, Park Inkeun, Kim Young Saing, Hong Junshik, Sym Sun Jin, Park Jinny, Lee Jae Hoon, Shin Dong Bok, Cho Eun Kyung

Abstract excerpt

INTRODUCTION: In patients with non-small cell lung cancer (NSCLC), the predictive value of rare epidermal growth factor receptor (EGFR) exon 20 mutations in determining a patient's response to EGFR tyrosine kinase inhibitor (TKI) treatment is unclear. PATIENTS AND METHODS: We reviewed data for NSCLC patients harboring EGFR exon 20 mutations from two hospitals in Korea. EGFR mutations were analyzed using...

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Identifiers

PMID: 25146938
DOI: 10.1007/s10637-014-0146-x

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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