Article
Prognostic Value of EGFR Exon-20 Insertions in Czech Patients With Advanced Non-small Cell Lung Cancer.
Anticancer research - 1 Nov 2021
Skrickova Jana, Pesek Milos, Opalka Petr, Koubkova Leona, Zemanova Milada, Hrnciarik Michal, Blazek Jiri, Svaton Martin, Krejci Jana, Coupkova Helena, Dolezal Daniel, Tuzova Tana, Holubec Lubos, Mahadevia Parthiv, Sandstrom Kristina, Kunovszki Peter, Barinova Magda, Hurdalkova Karolina, Fischer Ondrej, Cernovska Marketa, Bratova Monika
Abstract excerpt
BACKGROUND/AIM: Per literature, patients with epidermal growth factor receptor (EGFR) exon-20 insertions respond poorly to tyrosine kinase inhibitors (TKIs). This study analyzed real-world data to examine the prognostic and predictive value of these mutations. PATIENTS AND METHODS: We conducted a retrospective cohort study using Czech TULUNG Registry data, with data on multiple mutation types, collected in...
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