A functional polymorphism in CSF1R gene is a novel susceptibility marker for lung cancer among never-smoking females.

doi:10.1097/JTO.0000000000000310

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Article

A functional polymorphism in CSF1R gene is a novel susceptibility marker for lung cancer among never-smoking females.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Nov 2014

Kang Hyo-Gyoung, Lee Shin Yup, Jeon Hyo-Sung, Choi Yi Young, Kim Soyoun, Lee Won Kee, Lee Hyun Chul, Choi Jin Eun, Bae Eun Young, Yoo Seung Soo, Lee Jaehee, Cha Seung Ick, Kim Chang Ho, Lee Myung Hoon, Kim Young Tae, Kim Jin Hee, Hong Yun-Chul, Kim Yeul Hong, Park Jae Yong

Abstract excerpt

INTRODUCTION: It has been estimated that the proportion of never-smokers among females with lung cancer is 53% worldwide and 75% in Korea. We conducted a two-stage study to identify genetic factors responsible for lung cancer susceptibility in female never-smokers. MATERIALS AND METHODS: In a discovery set, 1969 potentially functional single nucleotide polymorphisms (SNPs) of 1151 genes, which were related to...

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PMID: 25144241
DOI: 10.1097/JTO.0000000000000310

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