Article
Linear population allocation by bistable switches in response to transient stimulation.
PloS one - 1 Jan 2014
Srimani Jaydeep K, Yao Guang, Neu John, Tanouchi Yu, Lee Tae Jun, You Lingchong
Abstract excerpt
Many cellular decision processes, including proliferation, differentiation, and phenotypic switching, are controlled by bistable signaling networks. In response to transient or intermediate input signals, these networks allocate a population fraction to each of two distinct states (e.g. OFF and ON). While extensive studies have been carried out to analyze various bistable networks, they are primarily focused on...
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