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Article

Molecular features and survival outcomes of the intrinsic subtypes within HER2-positive breast cancer.

Journal of the National Cancer Institute - 1 Aug 2014

Prat Aleix, Carey Lisa A, Adamo Barbara, Vidal Maria, Tabernero Josep, Cortés Javier, Parker Joel S, Perou Charles M, Baselga José

Abstract excerpt

BACKGROUND: The clinical impact of the biological heterogeneity within HER2-positive (HER2+) breast cancer is not fully understood. Here, we evaluated the molecular features and survival outcomes of the intrinsic subtypes within HER2+ breast cancer. METHODS: We interrogated The Cancer Genome Atlas (n = 495) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) datasets (n = 1730) of primary...

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Identifiers

PMID: 25139534
DOI: 10.1093/jnci/dju152
PMCID: PMC4151853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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