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Article

Invasive Breast Cancer: Recognition of Molecular Subtypes

1 Jan 2011

Abstract excerpt

SUMMARY: Molecular profiling has fundamentally changed our understanding of breast cancer in the last 10 years, by creating a new taxonomy of breast cancers based on the expression patterns of so-called 'intrinsic genes'. Hierarchical clustering analyses performed on microarray-based gene expression profiles of breast cancers defined distinct breast cancer subgroups (luminal type A/B, HER2-enriched type,...

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PMID: 22135623
DOI: 10.1159/000331339

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