Article
Mitochondriome and cholangiocellular carcinoma.
PloS one - 1 Jan 2014
Bahitham Wesam, Liao Xiaoping, Peng Fred, Bamforth Fiona, Chan Alicia, Mason Andrew, Stone Bradley, Stothard Paul, Sergi Consolato
Abstract excerpt
Cholangiocellular carcinoma (CCA) of the liver was the target of more interest, recently, due mainly to its increased incidence and possible association to new environmental factors. Somatic mitochondrial DNA (mtDNA) mutations have been found in several cancers. Some of these malignancies contain changes of mtDNA, which are not or, very rarely, found in the mtDNA databases. In terms of evolutionary genetics and...
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