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Article

IFNG and autophagy

27 Aug 2012

Abstract excerpt

IFNG/IFNγ plays a critical role in driving innate and acquired defenses against infectious pathogens. The death-associated protein kinase 1 (DAPK1), originally identified as an activator of IFNG-induced cell death, controls autophagy. Previously, we have shown that transcription factor CEBPB (C/EBP-β) regulates IFNG-induced expression of Dapk1 through a CRE/ATF motif in its enhancer. In this paper we have shown...

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PMID: 22874566
DOI: 10.4161/auto.21403

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