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Association of ADAM33 Gene rs2280091 (T1) Polymorphism with Asthma Severity in Syrian Population: A Case-Control Study Using PCR-RFLP Analysis

2025-07-18

Abstract excerpt

<h4>Background</h4> Asthma is a complex chronic inflammatory disease affecting approximately 339 million people worldwide. The ADAM33 gene, encoding a disintegrin and metalloproteinase, has emerged as a key susceptibility gene for asthma, with the rs2280091 (T1) polymorphism showing variable associations across different populations. This study represents the first genetic investigation of asthma in the Syrian po...

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Literature Corpus work: ce6c1957-d3ef-567e-9878-78a3a69b0474
DOI: 10.1101/2025.07.17.25331673

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