Article
Human liver stem/progenitor cells decrease serum bilirubin in hyperbilirubinemic Gunn rat.
World journal of gastroenterology - 14 Aug 2014
Maerckx Cédric, Tondreau Tatiana, Berardis Silvia, van Pelt Jos, Najimi Mustapha, Sokal Etienne
Abstract excerpt
AIM: To test the ability of adult-derived human liver stem/progenitor cells (ADHLSC) from large scale cultures to conjugate bilirubin in vitro and in bilirubin conjugation deficient rat. METHODS: ADHLSC from large scale cultures were tested for their phenotype and for their capacity to conjugate bilirubin in vitro after hepatogenic differentiation. In vivo, Gunn rats [uridine diphosphate-glucuronosyltransferase...
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