Article
Molecular analysis of intraspousal transmission of hepatitis C virus.
Journal of hepatology - 1 Apr 1995
Chayama K, Kobayashi M, Tsubota A, Koida I, Arase Y, Saitoh S, Ikeda K, Kumada H
Abstract excerpt
BACKGROUND/AIMS: Although intraspousal transmission of hepatitis C virus (HCV) has been speculated, there is no direct evidence. METHODS: To investigate whether transmission of HCV occurs by this route, 295 spouses of persons diagnosed with HCV were studied. Of these, 25 (8.8%) tested positive for anti-HCV. Next, the HCV genotype was determined by polymerase chain reaction using a mixed primer set, and cDNA was...
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