Article
Tracing the history of hepatitis B virus genotype D in western Japan.
Journal of medical virology - 1 Jan 2006
Michitaka Kojiro, Tanaka Yasuhito, Horiike Norio, Duong Tran Nhu, Chen Yan, Matsuura Kana, Hiasa Yoichi, Mizokami Masashi, Onji Morikazu
Abstract excerpt
The major hepatitis B virus (HBV) genotypes in Japan are B and C. HBV genotype D (HBV/D), however, is widespread in a small area of Western Japan, where the Gianotti-Crosti syndrome caused by HBV subtype ayw, which is suspected to be HBV/D, was endemic in the 1970s. The aim of the study was to elucidate its origin, time of transmission, and spread in this area. Genotyping of HBV-DNA was done in 363 patients with...
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