IFN-γ CA microsatellite polymorphism is associated with susceptibility to respiratory syncytial virus Infection and severity.

doi:10.1111/apa.12767

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Article

IFN-γ CA microsatellite polymorphism is associated with susceptibility to respiratory syncytial virus Infection and severity.

Acta paediatrica (Oslo, Norway : 1992) - 1 Dec 2014

Huang Jianfeng, Zhang Mingzhi, Zhang Xiaobo, Lu Aizhen, Wang Libo, Chen Chao

Abstract excerpt

AIM: IFN-γ, an essential cytokine in the viral cell-mediated immune response, has been associated with the pathogenesis of respiratory syncytial virus (RSV) bronchiolitis and to the severity of the infection. The aim of this study was to investigate whether IFN-γ CA microsatellite (rs3138557) polymorphism was associated with susceptibility to RSV in Chinese Han children and with the severity of the infection....

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PMID: 25130433
DOI: 10.1111/apa.12767

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