Article
[Association of INF-gamma/A+874T gene polymorphisms with respiratory syncytial virus bronchiolitis].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 Jan 2009
Dong Lin, Huang Zhi-Ying, Chen Xiao-Fang, Zhou Xiao-Cong, Li Jin-Yan, Lin Jian
Abstract excerpt
OBJECTIVE: A deficient interferon-gamma (IFN-gamma) response has been involved in the pathogenesis of severe respiratory syncytial virus (RSV) infection. Gene polymorphisms in IFN-gamma/A+874T have been associated with the susceptibility to asthma and might be related to disease severity of RSV infection. This study investigated the single nucleotide polymorphisms (SNPs) of IFN-gamma/A+874T in Han children in...
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