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Article

Polymorphisms in melanoma differentiation‐associated gene 5 link protein function to clearance of hepatitis C virus

30 Jul 2014

Abstract excerpt

UNLABELLED: Among patients newly infected with hepatitis C virus (HCV), only 20-30% clear the infection spontaneously. In the remaining 70% the infection persists, causing chronic liver inflammation and disease. It is well established that polymorphisms in host genes, especially in components of the innate immune response, contribute to the phenomenon of spontaneous HCV clearance. Retinoic acid inducible gene-I...

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PMID: 25130193
DOI: 10.1002/hep.27344

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