Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in toll-like receptors and retinoic acid-inducible gene I and outcome of hepatitis C virus infection: a candidate gene association study.

Journal of viral hepatitis - 1 Aug 2014

Clausen L N, Ladelund S, Weis N, Bukh J, Benfield T

Abstract excerpt

We evaluated the effects of genetic variation in toll-like receptors (TLR), retinoic acid-inducible gene I (RIG-I) and their signalling pathways on spontaneous hepatitis C virus (HCV) resolution. We screened 95 single-nucleotide polymorphisms (SNPs) in 22 genes. SNPs significantly associated with resolution in the discovery cohort were genotyped in a validation cohort. Multivariate logistic regression adjusted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DEAD Box Protein 58
Share to DEAD-box RNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Resistance

Share to Hepatitis C

Share to I-kappa B Kinase

Share to Linkage Disequilibrium

Share to Receptors, Immunologic

Share to Toll-Like Receptors

Source

Identifiers

PMID: 24224717
DOI: 10.1111/jvh.12188

Genes

TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in toll-like receptors and retinoic acid-inducible gene I and outcome of hepatitis C virus infection: a candidate gene association study.PMID 24224717Read ↗

Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts.Semantic proximity Read ↗

A systematic review and meta-analysis of HCV clearance.Semantic proximity Read ↗

Influence of IFNL3.rs12979860 and IFNL4.ss469415590 polymorphism on clearance of hepatitis C virus infection among Egyptians.Semantic proximity Read ↗

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.Semantic proximity Read ↗

The interaction of genetic determinants in the outcome of HCV infection: evidence for discrete immunological pathways.Semantic proximity Read ↗

Polymorphisms in melanoma differentiation‐associated gene 5 link protein function to clearance of hepatitis C virusSemantic proximity Read ↗

Polymorphisms of RIG-I-like receptor influence HBV clearance in Chinese Han population.Semantic proximity Read ↗

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus.Semantic proximity Read ↗

Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection.Semantic proximity Read ↗

Polymorphisms in the Th17 cell-related RORC gene are associated with spontaneous clearance of HCV in Chinese women.Semantic proximity Read ↗

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.Semantic proximity Read ↗

Genetic Variation in the IL-6 and HLA-DQB1 Genes Is Associated with Spontaneous Clearance of Hepatitis C Virus Infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.