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Article

CD86 polymorphism affects pneumonia-induced sepsis by decreasing gene expression in monocytes.

Inflammation - 1 Apr 2015

Song Haihan, Tang Lunxian, Xu Mingzheng, Li Hongqiang, Xu Shumin, Li Guanggang, Bao Xiaowei, Sun Bingke, Cheng Tingting, Yang Qian, Bai Jianwen

Abstract excerpt

Sepsis, a clinical syndrome occurring in patients following infection or injury, is a leading cause of morbidity and mortality worldwide. CD86 (B7-2) is a costimulatory molecule on antigen-presenting cells and plays critical roles in immune responses. In the current study, we investigated the association of two CD86 polymorphisms, rs1129055G/A and rs17281995G/C, with susceptibility to pneumonia-induced sepsis and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25129060
DOI: 10.1007/s10753-014-9997-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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