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Article

Core mutations, IL28B polymorphisms and response to peginterferon/ribavirin treatment in Swedish patients with hepatitis C virus genotype 1 infection.

BMC infectious diseases - 12 May 2011

Alestig Erik, Arnholm Birgitta, Eilard Anders, Lagging Martin, Nilsson Staffan, Norkrans Gunnar, Wahlberg Thomas, Wejstål Rune, Westin Johan, Lindh Magnus

Abstract excerpt

BACKGROUND: Patients infected with hepatitis C virus (HCV) genotype 1 respond poorly to standard treatment with 50% or less achieving sustained virologic response. Predicting outcome is essential and could help avoid unnecessary treatment and reduce health cost. Recently, an association of amino acid substitutions in the core region and treatment outcome was observed in Japanese patients. In the present study,...

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Identifiers

PMID: 21569441
DOI: 10.1186/1471-2334-11-124
PMCID: PMC3112098

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Core mutations, IL28B polymorphisms and response to peginterferon/ribavirin treatment in Swedish patients with hepatitis C virus genotype 1 infection.PMID 21569441Read ↗

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