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Article

HIV-1 transgenic rats display alterations in immunophenotype and cellular responses associated with aging.

PloS one - 1 Jan 2014

Abbondanzo Susan J, Chang Sulie L

Abstract excerpt

Advances in anti-retroviral therapy over the last two decades have allowed life expectancy in patients infected with the human immunodeficiency virus to approach that of the general population. The process of aging in mammalian species, including rats, results in immune response changes, alterations in immunological phenotypes, and ultimately increased susceptibility to many infectious diseases. In order to...

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PMID: 25127062
DOI: 10.1371/journal.pone.0105256
PMCID: PMC4134284

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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