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Article

Sunlight exposure, pigmentation, and incident age-related macular degeneration.

Investigative ophthalmology & visual science - 14 Aug 2014

Klein Barbara E K, Howard Kerri P, Iyengar Sudha K, Sivakumaran Theru A, Meyers Kristin J, Cruickshanks Karen J, Klein Ronald

Abstract excerpt

PURPOSE: Examine potential effects of sunlight exposure, hair color, eye color, and selected gene single-nucleotide polymorphisms (SNPs) on incidence of AMD. METHODS: Subjects participated in up to five examinations over a 20-year period. Eye color, self-reported hair color as a teenager, and sunlight exposure were ascertained at the baseline examination. Presence and severity of AMD and its lesions were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25125603
DOI: 10.1167/iovs.14-14602
PMCID: PMC4165367

Genes

HERC2
OCA2
ARMS2
CFH

Variants

rs1061170
rs1061170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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