Genetic determinants of hair, eye and skin pigmentation in Europeans.

doi:10.1038/ng.2007.13

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Article

Genetic determinants of hair, eye and skin pigmentation in Europeans.

Nature genetics - 1 Dec 2007

Sulem Patrick, Gudbjartsson Daniel F, Stacey Simon N, Helgason Agnar, Rafnar Thorunn, Magnusson Kristinn P, Manolescu Andrei, Karason Ari, Palsson Arnar, Thorleifsson Gudmar, Jakobsdottir Margret, Steinberg Stacy, Pálsson Snaebjörn, Jonasson Fridbert, Sigurgeirsson Bardur, Thorisdottir Kristin, Ragnarsson Rafn, Benediktsdottir Kristrun R, Aben Katja K, Kiemeney Lambertus A, Olafsson Jon H, Gulcher Jeffrey, Kong Augie, Thorsteinsdottir Unnur, Stefansson Kari

Abstract excerpt

Hair, skin and eye colors are highly heritable and visible traits in humans. We carried out a genome-wide association scan for variants associated with hair and eye pigmentation, skin sensitivity to sun and freckling among 2,986 Icelanders. We then tested the most closely associated SNPs from six regions--four not previously implicated in the normal variation of human pigmentation--and replicated their...

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PMID: 17952075
DOI: 10.1038/ng.2007.13

Genes

KITLG
OCA2
TYR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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