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Article

Use of the l1 norm for selection of sparse parameter sets that accurately predict drug response phenotype from viral genetic sequences.

AMIA ... Annual Symposium proceedings. AMIA Symposium - 1 Jan 2005

Matthew Rabinowitz, Banjevic Milena, Chan A S, Myers Lance, Wolkowicz Roland, Haberer Jessica, Singer Joshua

Abstract excerpt

We describe the use of the l1 norm for selection of a sparse set of model parameters that are used in the prediction of viral drug response, based on genetic sequence data of the Human Immunodeficiency Virus (HIV) reverse-transcriptase enzyme. We discuss the use of the l1 norm in the Least Absolute Selection and Shrinkage Operator (LASSO) regression model and the Support Vector Machine model. When tested by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16779091
PMCID: PMC1560612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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