Article
Control of Toll-like receptor-mediated T cell-independent type 1 antibody responses by the inducible nuclear protein IκB-ζ.
The Journal of biological chemistry - 7 Nov 2014
Hanihara-Tatsuzawa Fumito, Miura Hanae, Kobayashi Shuhei, Isagawa Takayuki, Okuma Atsushi, Manabe Ichiro, MaruYama Takashi
Abstract excerpt
Antibody responses have been classified as being either T cell-dependent or T cell-independent (TI). TI antibody responses are further classified as being either type 1 (TI-1) or type 2 (TI-2), depending on their requirement for B cell-mediated antigen receptor signaling. Although the mechanistic basis of antibody responses has been studied extensively, it remains unclear whether different antibody responses...
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