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Article

Global genetic variations predict brain response to faces.

PLoS genetics - 1 Aug 2014

Dickie Erin W, Tahmasebi Amir, French Leon, Kovacevic Natasa, Banaschewski Tobias, Barker Gareth J, Bokde Arun, Büchel Christian, Conrod Patricia, Flor Herta, Garavan Hugh, Gallinat Juergen, Gowland Penny, Heinz Andreas, Ittermann Bernd, Lawrence Claire, Mann Karl, Martinot Jean-Luc, Nees Frauke, Nichols Thomas, Lathrop Mark, Loth Eva, Pausova Zdenka, Rietschel Marcela, Smolka Michal N, Ströhle Andreas, Toro Roberto, Schumann Gunter, Paus Tomáš

Abstract excerpt

Face expressions are a rich source of social signals. Here we estimated the proportion of phenotypic variance in the brain response to facial expressions explained by common genetic variance captured by ∼ 500,000 single nucleotide polymorphisms. Using genomic-relationship-matrix restricted maximum likelihood (GREML), we related this global genetic variance to that in the brain response to facial expressions, as...

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Identifiers

PMID: 25122193
DOI: 10.1371/journal.pgen.1004523
PMCID: PMC4133042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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