Article
Amygdala hyperreactivity to faces conditioned with a social-evaluative meaning- a multiplex, multigenerational fMRI study on social anxiety endophenotypes.
NeuroImage. Clinical - 1 Jan 2020
Bas-Hoogendam Janna Marie, van Steenbergen Henk, van der Wee Nic J A, Westenberg P Michiel
Abstract excerpt
Social anxiety disorder (SAD) runs in families, but the neurobiological pathways underlying the genetic susceptibility towards SAD are largely unknown. Here, we employed an endophenotype approach, and tested the hypothesis that amygdala hyperreactivity to faces conditioned with a social-evaluative meaning is a candidate SAD endophenotype. We used data from the multiplex, multigenerational Leiden Family Lab study...
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