Article
Clinicopathological features of rare BRAF mutations in Korean thyroid cancer patients.
Journal of Korean medical science - 1 Aug 2014
Cho Uiju, Oh Woo Jin, Bae Ja Seong, Lee Sohee, Lee Young Sub, Park Gyeong Sin, Lee Youn Soo, Jung Chan Kwon
Abstract excerpt
The most common BRAF mutation in thyroid cancer is c.1799T>A (p.Val600Glu), and other BRAF mutations are rarely reported. We investigated the clinicopathological features of thyroid cancer with rare BRAF mutations. A total of 2,763 patients with thyroid cancer underwent molecular testing by direct DNA sequencing for mutations in BRAF exon 15. Among them, 2,110 (76.4%) had BRAF mutations. The c.1799T>A mutation...
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