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Article

Biophysical characterisation of calumenin as a charged F508del-CFTR folding modulator.

PloS one - 1 Jan 2014

Tripathi Rashmi, Benz Nathalie, Culleton Bridget, Trouvé Pascal, Férec Claude

Abstract excerpt

The cystic fibrosis transmembrane regulator (CFTR) is a cyclic-AMP dependent chloride channel expressed at the apical surface of epithelial cells lining various organs such as the respiratory tract. Defective processing and functioning of this protein caused by mutations in the CFTR gene results in loss of ionic balance, defective mucus clearance, increased proliferation of biofilms and inflammation of human...

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Share to Calcium-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25120007
DOI: 10.1371/journal.pone.0104970
PMCID: PMC4132023

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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