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Article

An in vivo model for the study of ovarian cancer and the persistence of characteristic mutations in xenografts.

European journal of gynaecological oncology - 1 Jan 2014

Li Y, Gu Y J, Liu C N, Yue T F

Abstract excerpt

OBJECTIVE: To identify factors affecting xenograft growth of epithelial ovarian cancer (EOC) cells in nude mice and to detect characteristic mutations occurring in the xenografts following serial passage. MATERIALS AND METHODS: A total of 64 human EOCs were subcutaneously inoculated in Balb/c nude mice in order to obtain a series of xenografts. Whole-exome sequencing was analyzed with Agilent SureSelect targeted...

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Source

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PMID: 25118479

Genes

BRAF
CTNNB1
PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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