Article
Reduced Expression of HLA-DR on Monocytes During Severe Respiratory Syncytial Virus Infections.
The Pediatric infectious disease journal - 1 Mar 2016
Ahout Inge M L, Jans Jop, Haroutiounian Lilid, Simonetti Elles R, van der Gaast-de Jongh Christa, Diavatopoulos Dimitri A, de Jonge Marien I, de Groot Ronald, Ferwerda Gerben
Abstract excerpt
BACKGROUND: Respiratory syncytial virus (RSV) is a common cause of bronchiolitis in infants with a wide spectrum of disease severity. Besides environmental and genetic factors, it is thought that the innate immune system plays a pivotal role. The aim of this study was to investigate the expression of immune receptors on monocytes and the in vitro responsiveness from infants with severe RSV infections. METHODS:...
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