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Article

Tick passage results in enhanced attenuation of Babesia bovis.

Infection and immunity - 1 Oct 2014

Sondgeroth Kerry S, McElwain Terry F, Ueti Massaro W, Scoles Glen A, Reif Kathryn E, Lau Audrey O T

Abstract excerpt

Serial blood passage of virulent Babesia bovis in splenectomized cattle results in attenuated derivatives that do not cause neurologic disease. Tick transmissibility can be lost with attenuation, but when retained, attenuated B. bovis can revert to virulence following tick passage. This study provides data showing that tick passage of the partially attenuated B. bovis T2Bo derivative strain further decreased...

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Identifiers

PMID: 25114111
DOI: 10.1128/IAI.02126-14
PMCID: PMC4187863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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