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Article

Study of virulence and vector transmission of Babesia bovis by use of cloned parasite lines.

Infection and immunity - 1 Jul 1990

Timms P, Stewart N P, De Vos A J

Abstract excerpt

Cloned lines of Babesia bovis were prepared from the avirulent vaccine strain, Ka, by an in vivo limiting dilution procedure. The virulence of these clones for adult Bos taurus cattle varied from completely avirulent to highly virulent. This suggests that the parent strain, Ka, is composed of a mixture of subpopulations of varied virulence. Passage of the avirulent clone K-19-47 in intact (nonsplenectomized)...

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Identifiers

PMID: 2365457
DOI: 10.1128/iai.58.7.2171-2176.1990
PMCID: PMC258793

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