Article
BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT.
Bone marrow transplantation - 1 Nov 2014
Piras Ignazio Stefano, Angius Andrea, Andreani Marco, Testi Manuela, Lucarelli Guido, Floris Matteo, Marktel Sarah, Ciceri Fabio, La Nasa Giorgio, Fleischhauer Katharina, Roncarolo Maria Grazia, Bulfone Alessandro, Gregori Silvia, Bacchetta Rosa
Abstract excerpt
The genetic background of donor and recipient is an important factor determining the outcome of allogeneic hematopoietic SCT (allo-HSCT). We applied whole-genome analysis to investigate genetic variants-other than HLA class I and II-associated with negative outcome after HLA-identical sibling allo-HSCT in a cohort of 110 β-Thalassemic patients. We identified two single-nucleotide polymorphisms (SNPs) in BAT2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
