Article
Heredity, molecular genetics and colorectal cancer: a review.
The Australian and New Zealand journal of surgery - 1 Feb 1993
Brewer D A, Bokey E L, Fung C, Chapuis P H
Abstract excerpt
It is estimated that the hereditary polyposis and non-polyposis colorectal cancer (CRC) syndromes, which have an autosomal dominant pattern of inheritance, represent less than 10% of the total CRC burden. Thus, more than 90% of all cases of CRC have previously been considered to arise 'sporadically', with no identifiable genetic link. However, recent clinical evidence now suggests that a significant proportion of...
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