Article
Heredity, molecular genetics and colorectal cancer: a review.
The Australian and New Zealand journal of surgery - 1 Feb 1993
Brewer D A, Bokey E L, Fung C, Chapuis P H
Abstract excerpt
It is estimated that the hereditary polyposis and non-polyposis colorectal cancer (CRC) syndromes, which have an autosomal dominant pattern of inheritance, represent less than 10% of the total CRC burden. Thus, more than 90% of all cases of CRC have previously been considered to arise 'sporadical...
Topics
- Colorectal Neoplasms
- Female
- Genes, Tumor Suppressor
- Humans
- Male
- Models, Genetic
- Mutation
- Oncogenes