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Article

Role of Ergothioneine in Microbial Physiology and Pathogenesis

9 Aug 2017

Abstract excerpt

SIGNIFICANCE: L-ergothioneine is synthesized in actinomycetes, cyanobacteria, methylobacteria, and some fungi. In contrast to other low-molecular-weight redox buffers, glutathione and mycothiol, ergothioneine is primarily present as a thione rather than a thiol at physiological pH, which makes it resistant to autoxidation. Ergothioneine regulates microbial physiology and enables the survival of microbes under...

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PMID: 28791878
DOI: 10.1089/ars.2017.7300

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