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Article

Modeling genome coverage in single-cell sequencing.

Bioinformatics (Oxford, England) - 15 Nov 2014

Daley Timothy, Smith Andrew D

Abstract excerpt

MOTIVATION: Single-cell DNA sequencing is necessary for examining genetic variation at the cellular level, which remains hidden in bulk sequencing experiments. But because they begin with such small amounts of starting material, the amount of information that is obtained from single-cell sequencing experiment is highly sensitive to the choice of protocol employed and variability in library preparation. In...

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Identifiers

PMID: 25107873
DOI: 10.1093/bioinformatics/btu540
PMCID: PMC4221128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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