Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: Phenotypic and mutational spectrum in patients from mainland China.

The International journal of neuroscience - 1 Jan 2015

Yin Xinzhen, Wu Dingwen, Wan Jinping, Yan Shenqiang, Lou Min, Zhao Guohua, Zhang Baorong

Abstract excerpt

AIMS: To analyze the NOTCH3 gene mutations in patients from mainland China clinically suspected to have cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and evaluate large intracranial arteries in CADASIL patients. METHODS: We performed clinical, neuroimaging and NOTCH3 gene (exons 2-23) examinations in 47 subjects from 34 families. Large intracranial arteries...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to CADASIL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Magnetic Resonance Angiography

Share to Magnetic Resonance Imaging

Share to Neurologic Examination

Share to Receptor, Notch3

Share to Receptors, Notch

Source

Identifiers

PMID: 25105908
DOI: 10.3109/00207454.2014.951929

Genes

NOTCH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: Phenotypic and mutational spectrum in patients from mainland China.PMID 25105908Read ↗

NOTCH3 mutations and clinical features in 33 mainland Chinese families with CADASIL.Semantic proximity Read ↗

Intracerebral Hemorrhage in Autosomal Dominant Cerebral Arteriopathy With Subcortical Infarcts and Leukoencephalopathy.Semantic proximity Read ↗

Genotypic and Phenotypic Characteristics of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy from China.Semantic proximity Read ↗

Population-specific spectrum of NOTCH3 mutations, MRI features and founder effect of CADASIL in Chinese.Semantic proximity Read ↗

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: two novel mutations in the NOTCH3 gene in Chinese.Semantic proximity Read ↗

Characterization of CADASIL among the Han Chinese in Taiwan: Distinct Genotypic and Phenotypic Profiles.Semantic proximity Read ↗

[NOTCH3 gene mutations in two Chinese families featuring cerebral autosomal dominant arteriopathy with subcortical infarct and leucoencephalopathy].Semantic proximity Read ↗

A Chinese CADASIL family with p.R578C mutation at exon 11 of the NOTCH3 gene.Semantic proximity Read ↗

Genetic spectrum of NOTCH3 and clinical phenotype of CADASIL patients in different populations.Semantic proximity Read ↗

[Clinical features in 4 Chinese families with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)].Semantic proximity Read ↗

Comparison of clinical, familial, and MRI features of CADASIL and NOTCH3-negative patients.Semantic proximity Read ↗

Pathogenesis and therapeutic advances of cerebral autosomal- dominant arteriopathy with subcortical infarcts and leukoencephalopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.