Article
[Clinical features in 4 Chinese families with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 1 Oct 2004
Lv He, Yao Sheng, Zhang Wei, Wang Zhao-xia, Huang Yi-ning, Niu Xiao-yuan, Zhang Zhuo, Yuan Yun
Abstract excerpt
OBJECTIVE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is an inherited cerebral arteriolar disease in adulthood, which is caused by NOTCH3 gene mutation. The main symptoms were migraine, cerebral stroke, later with mood disorders and dementia in Caucasian patients. Recently, the disease was also recognized in Asian patients, in whom the migraine is rarely...
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