Article
Pathogenesis and therapeutic advances of cerebral autosomal- dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Yi chuan = Hereditas - 20 Jul 2023
Zhang Yi, Wu Zhi-Ying
Abstract excerpt
Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common hereditary cerebral small vessel disease in adults. Many CADASIL cases were reported after NOTCH3 was identified as the causative gene of CADASIL. However, there is still no specific and effective therapies for CADASIL. In this review, we summarize recent research progress on disease models,...
Topics
- Adult
- Humans
- CADASIL
- Leukoencephalopathies
- Magnetic Resonance Imaging
- Mutation