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Article

Characterization of CADASIL among the Han Chinese in Taiwan: Distinct Genotypic and Phenotypic Profiles.

PloS one - 1 Jan 2015

Liao Yi-Chu, Hsiao Cheng-Tsung, Fuh Jong-Ling, Chern Chang-Ming, Lee Wei-Ju, Guo Yuh-Cherng, Wang Shuu-Jiun, Lee I-Hui, Liu Yo-Tsen, Wang Yen-Feng, Chang Feng-Chi, Chang Ming-Hung, Soong Bing-Wen, Lee Yi-Chung

Abstract excerpt

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is originally featured with a strong clustering of mutations in NOTCH3 exons 3-6 and leukoencephalopathy with frequent anterior temporal pole involvement. The present study aims at characterizing the genotypic and phenotypic profiles of CADASIL in Taiwan. One hundred and twelve patients with CADASIL from 95...

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Identifiers

PMID: 26308724
DOI: 10.1371/journal.pone.0136501
PMCID: PMC4550240

Genes

NOTCH3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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