Article
Genetic deletion in uncoupling protein 3 augments 18F-fluorodeoxyglucose cardiac uptake in the ischemic heart.
BMC cardiovascular disorders - 8 Aug 2014
Gargiulo Sara, Petretta Maria Piera, Greco Adelaide, Panico Mariarosaria, Larobina Michele, Gramanzini Matteo, Schiattarella Gabriele G, Esposito Giovanni, Petretta Mario, Brunetti Arturo, Cuocolo Alberto
Abstract excerpt
BACKGROUND: We investigated the effects of uncoupling protein 3 (UCP3) genetic deletion on 18F-fluorodeoxyglucose (FDG) cardiac uptake by positron emission tomography (PET)/computed tomography (CT) dedicated animal system after permanent coronary artery ligation. METHODS: Cardiac 18F-FDG PET/CT was performed in UCP3 knockout (UCP3-/-) and wild-type (WT) mice one week after induction of myocardial infarction or...
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