Article
Relationship between chain collapse and secondary structure formation in a partially folded protein.
Biopolymers - 1 Jun 2014
Nakagawa Kanako, Yamada Yoshiteru, Matsumura Yoshitaka, Tsukamoto Seiichi, Yamamoto-Ohtomo Mio, Ohtomo Hideaki, Okabe Takahiro, Fujiwara Kazuo, Ikeguchi Masamichi
Abstract excerpt
Chain collapse and secondary structure formation are frequently observed during the early stages of protein folding. Is the chain collapse brought about by interactions between secondary structure units or is it due to polymer behavior in a poor solvent (coil-globule transition)? To answer this question, we measured small-angle X-ray scattering for a series of β-lactoglobulin mutants under conditions in which...
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