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Article

Generation of fertile and fecund F0 XY female mice from XY ES cells.

Transgenic research - 1 Feb 2015

Kuno Junko, Poueymirou William T, Gong Guochun, Siao Chia-Jen, Clarke Georgia, Esau Lakeisha, Kojak Nada, Posca Julita, Atanasio Amanda, Strein John, Yancopoulos George D, Lai Ka-Man Venus, DeChiara Thomas M, Frendewey David, Auerbach Wojtek, Valenzuela David M

Abstract excerpt

Known examples of male to female sex reversal in mice are caused by either strain incompatibilities or mutations in genes required for male sex determination. The resultant XY females are often sterile or exhibit very poor fertility. We describe here embryonic stem (ES) cell growth conditions that promote the production of healthy, anatomically normal fertile and fecund female F0 generation mice completely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25087174
DOI: 10.1007/s11248-014-9815-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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