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Article

Cellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study: correlation with coagulopathy.

Thrombosis research - 1 Sept 2014

Matijevic Nena, Wang Yao-Wei W, Wade Charles E, Holcomb John B, Cotton Bryan A, Schreiber Martin A, Muskat Peter, Fox Erin E, Del Junco Deborah J, Cardenas Jessica C, Rahbar Mohammad H, Cohen Mitchell Jay

Abstract excerpt

BACKGROUND: Trauma-induced coagulopathy following severe injury is associated with increased bleeding and mortality. Injury may result in alteration of cellular phenotypes and release of cell-derived microparticles (MP). Circulating MPs are procoagulant and support thrombin generation (TG) and clotting. We evaluated MP and TG phenotypes in severely injured patients at admission, in relation to coagulopathy and...

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Identifiers

PMID: 25086657
DOI: 10.1016/j.thromres.2014.07.023
PMCID: PMC4160305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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