Differentiating disseminated intravascular coagulation (DIC) with the fibrinolytic phenotype from coagulopathy of trauma and acute coagulopathy of trauma-shock (COT/ACOTS).

Abstract excerpt

Two concepts have been proposed for the hemostatic changes occurring early after trauma. Disseminated intravascular coagulation (DIC) with the fibrinolytic phenotype is characterized by activation of the coagulation pathways, insufficient anticoagulant mechanisms and increased fibrinolysis. Coagulopathy of trauma and acute coagulopathy of trauma-shock (COT/ACOTS) occurs as a result of increased activation of the...

Topics

• Blood Coagulation Disorders
• Diagnosis, Differential
• Disseminated Intravascular Coagulation
• Fibrinolysis
• Hemostasis
• Humans
• Phenotype
• Shock, Traumatic
• Wound Healing