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Glucocorticoid receptors in the retina, Müller glia and the formation of Müller glia-derived progenitors

2 Aug 2014

Abstract excerpt

Identification of the signaling pathways that influence the reprogramming of Müller glia into neurogenic retinal progenitors is key to harnessing the potential of these cells to regenerate the retina. Glucocorticoid receptor (GCR) signaling is commonly associated with anti-inflammatory responses and GCR agonists are widely used to treat inflammatory diseases of the eye, even though the cellular targets and...

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Share to Neuroinflammation and Neurodegeneration Mechanisms
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PMID: 25085975
DOI: 10.1242/dev.109835

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