Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Olig2 labeling index is correlated with histological and molecular classifications in low-grade diffuse gliomas.

Journal of neuro-oncology - 1 Nov 2014

Suzuki Aya, Nobusawa Sumihito, Natsume Atsushi, Suzuki Hiromichi, Kim Young-Ho, Yokoo Hideaki, Nagaishi Masaya, Ikota Hayato, Nakazawa Takuro, Wakabayashi Toshihiko, Ohgaki Hiroko, Nakazato Yoichi

Abstract excerpt

Diagnosis of low-grade diffuse gliomas based on morphology is highly subjective and, therefore, is often difficult, with significant intra- and interobserver variability. Here, we investigated WHO grade II diffuse astrocytomas, oligoastrocytomas and oligodendrogliomas for immunohistochemical expression of Olig2, measuring its labeling index (LI), and evaluated the significance of Olig2 LI in the histological and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Transcription Factors
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 1

Share to Glioma

Share to Isocitrate Dehydrogenase

Share to Loss of Heterozygosity

Share to Neoplasm Grading

Share to Oligodendrocyte Transcription Factor 2

Source

Identifiers

PMID: 25085214
DOI: 10.1007/s11060-014-1568-1

Genes

IDH1
ATRX
CIC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Olig2 labeling index is correlated with histological and molecular classifications in low-grade diffuse gliomas.PMID 25085214Read ↗

Molecular classification of low-grade diffuse gliomas.Semantic proximity Read ↗

Clarifying the diffuse gliomas: an update on the morphologic features and markers that discriminate oligodendroglioma from astrocytoma.Semantic proximity Read ↗

Prognostic Relevance of Histomolecular Classification of Diffuse Adult High-Grade Gliomas with Necrosis.Semantic proximity Read ↗

Cellular and molecular characterization of IDH1-mutated diffuse low grade gliomas reveals tumor heterogeneity and absence of EGFR/PDGFRα activation.Semantic proximity Read ↗

IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas.Semantic proximity Read ↗

Identification of CRYAB <sup>+</sup> KCNN3 <sup>+</sup> SOX9 <sup>+</sup> astro-like and EGFR <sup>+</sup> PDGFRA <sup>+</sup> OLIG1 <sup>+</sup> oligo-like tumoral cells in diffuse low-grade gliomas and implication of Notch1 signalling in their genesisSemantic proximity Read ↗

[Occurrence and molecular pathology of low grade gliomas].Semantic proximity Read ↗

Prognostic impact of the 2016 WHO classification of diffuse gliomas in the French POLA cohort.Semantic proximity Read ↗

Oligodendrocyte lineage genes ( <i>OLIG</i> ) as molecular markers for human glial brain tumorsSemantic proximity Read ↗

IDH1/2 mutation is a prognostic marker for survival and predicts response to chemotherapy for grade II gliomas concomitantly treated with radiation therapy.Semantic proximity Read ↗

Alpha Internexin: A Surrogate Marker for 1p/19q Codeletion and Prognostic Marker in Anaplastic (WHO grade III) Gliomas.Semantic proximity Read ↗

Dual-Genotype Diffuse Low-Grade Glioma: Is It Really Time to Abandon Oligoastrocytoma As a Distinct Entity?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.