Article
The PAI-1 4G/5G and ACE I/D polymorphisms and risk of recurrent pregnancy loss: a case-control study.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 2014
Kim Jin Ju, Choi Young Min, Lee Sung Ki, Yang Kwang Moon, Paik Eun Chan, Jeong Hyeon Jeong, Jun Jong Kwan, Han Ae Ra, Hong Min A
Abstract excerpt
PROBLEM: Thrombophilia has been postulated to be a contributor to the pathophysiology of recurrent pregnancy loss (RPL). We investigated the role of the plasminogen activator inhibitor type 1 (PAI-1) 4G/5G and angiotensin converting enzyme (ACE) I/D polymorphisms in Korean patients with RPL. METHOD OF STUDY: Genotyping was performed using the TaqMan assay in 227 RPL patients and 304 controls. RESULTS: The...
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